Research progress of nano-hydroxyapatite and its composite materials as drug carriers

Nano-hydroxyapatite (HAp) is an ideal inorganic drug carrier due to its good biological activity and drug adsorption ability. In this paper, the drug loading performance of nano-HAp was described by three aspects: Biological safety, antitumor activity and drug adsorption. Moreover, the effect of HAp micromorphology on drug-loading performance was also discussed. Furthermore, the classification, preparation, drug loading and drug release of nano-HAp composites were systematic reviewed, which aimed to provide a theoretical basis for application as drug carrier of nano-HAp and its composites.